Equipment
Stem Cell and Cryo Technology & Bioprocessing and Bioanalytics
Mobile epidemiological laboratories including BSL2 area for site-flexible performance of medical examinations and anthropometric measurements, collection of human samples, sample characterization, sample processing, clinical chemical analysis and LIN-based cryopreservation
Safety class S2 and S3 laboratories with lock areas for microbiological, molecular biological, cell biological and virological work
- cell culture robots (e. g. Tecan Freedom, TAP)
- various transmitted and reflected light microscopes with phase and differential
- interference contrast, fluorescence, manipulation and documentation unit and incubation chamber (e. g. Nikon, EVOS)
- transmitted light and fluorescence microscope with z-axis adjustable sample
- stage for 3D imaging of biological samples (Zeiss AxioObserver Z1)
- confocal microscope equipped with white light laser and continuous wave laser of wavelength 405 nm (Leica-TCS-SP8-X)
- live cell imaging units (e. g. Nikon BioStation-IM)
- HPLC system (Agilent 1260 Infinity Series)
- mass spectrometer (Q Exactive FOCUS)
- asymmetric field flow fractionation system with DLS and MALS detector
- flow cytometer including sorting unit (e.g. FACSAria, FACSCanto BD
- spectrophotometer for absorbance, fluorescence and luminescence measurements in microtiter plates
- TER impedance measurement systems (cellZscope®, Ussing chamber®) for transport studies and barrier function analysis of liquid-liquid interfaces
- Franz Cell System® (air-liquid interface model, e.g. skin barrier)
- aerosol exposure system VITROCELL® Cloud (air-liquid interface model, e. g. lung barrier)
- bioprinter for tissue engineering (Rokit invivo) and µContact printing (GeSiM µCP)
- various pipetting robots (GeSim Nanoplotter, Integra ViaFlo)
- ZetaSizer ® Nano
- gel electrophoresis units for DNA, RNA and proteins with documentation units (e. g. Bioanalyzer, Agilent)
- Western blot unit (BioRad)
- real time PCR system (QuantStudio 7, Applied Biosystems) and NanoDrop 2000 (Peqlab)
- freezing microtome
Laboratory for automation of stem cell processes and material characterization (Würzburg)
- Suspension bioreactors (OLS, CERO)
- multi-electrode array and impedance measurement system for electro-physiological studies (Axion Biosystems, Maestro Pro)
- automated cell counters (Chemometec, Nucleocounter)
- osmometers (Gonotec, Osmomat 3000)
- refractometers (Kern Optics, Abbe)
- spectrophotometer (Thermo ScientificTM NanodropTM One) for determination of DNA concentration
- rheometer for viscosity measurements (Anton Paar, MCR102)
- nano-indenter for the investigation of mechanical material properties (Optics11 Life, Pavone)
- plasma pen for surface modification (neoplas GmbH, kINPen)
- 3D printer (ROKIT, 3D Bioprinter INVIVO)
Optics laboratory for the operation and development of optical measurement technology
- ultra-short pulsed Ti:sapphire laser, various other pulsed and cw laser sources
- confocal Raman microscopy, Raman microspectrometry
- multiphoton laser scanning microscope (Miltenyi TrimScope Matrix)
- UV/Vis/NIR spectrometer (Perkin Elmer Lambda 950)
- fluorescence spectrometer (Hitachi FL4500)
- dynamic differential calorimetry (Perkin Elmer DSC8500), operable from -180°C to 600°C
Cryolab for preservation of biological samples in conventional and vitrification-based methods
- Askion C-line automated biobank and manual nitrogen-based storage tanks
- cryogenic workbenches for work below 80°C (Askion)
- controlled freezing equipment (e. g. SyLab, ViaFreeze Asysmtote)
- temperature control units for controlled thawing (e. g. Thawstar BioCision)
- freeze dryer (Martin Christ)
- programmable cryogenic chambers for microscopy (Cryostage Linkam)
Microsystems technology
- coating/microstructuring
- photolithography
- dry etching equipment (RIE) and wet chemical etching
- coating (sputtering (metals, piezoelectric coatings), PECVD: silicon dioxide, silicon nitride, deposition of Parylene C)
- imidization of polyimide
- wafer saw
- 3D printer
- silicone molding
- packaging and interconnection technologies (bonding, encapsulation, wire bonding)
- printing technologies
- screen printing (thick film pastes on ceramics, graphene-based ink on polymer films)
- roll-to-roll printing on polymer films (graphene-based ink, protein inks)
- inkjet printing on polymer films and glass (carbon and metal inks)
- 3D CAD (SolidWorks)